This session explores how PMOs evolve from project oversight to strategic enablers and true catalysts of business value in the age of AI. Based on real-world experience, it shows how to translate strategy into execution by aligning initiatives with data, AI, and business outcomes. Participants will gain a practical perspective on moving from AI experimentation to enterprise impact, balancing technology, governance, and value creation. The session also reflects on the PMO's role in enabling adoption, ensuring compliance, and shaping the right mindset and skills. The key message: sustainable impact comes from orchestrating strategy, governance, and value, not from algorithms alone.